A low volume spacer meant to be used with pMDI and/or nebulizers with a mechanical ventilation circuit

Developed to be used within both invasive and non-invasive mechanical ventilation circuits for pediatric care, the MinimHal® spacer allows the use of pMDI and vibrating mesh nebuliser to be used simultaneously.

Specifications

Benefits 

Scientific publications

The MinimHal® spacer charactéristic

Aimed to be used in a mechanical ventilation circuit, the MinimHal® spacer improves the drugs deposition into the lungs of patients under respiratory assistance, especially in pediatrics units. This device allows the use of pMDI and vibrating mesh nebuliser simultaneously.

Device description and intended use

MinimHal® is a spacer which can be plugged in different positions into mechanical ventilation circuits (invasive or non-invasive). The low volume of the MinimHal® make it especially for pediatric cares.

This new device improves lung deposition. It also helps the caregivers by reducing the number of ventilation circuits handlings, especially while changing the type of drugs delivery (pMDI and nebulizer).

The MinimHal® spacer is meant for children treated in Intensive Care Units (ICU) or under respiratory assistance.

Whose is MinimHal® aimed for?

The MinimHal® inhalation device has been especially designed for young patients who need to be treated by inhaled therapy through a respiratory assistance. It is used, in particular, to administrate inhaled bronchodilators, anti-inflammatory and antibiotics for ventilated patients.

Operating principles of the MinimHal® spacer

MinimHal® is intended to be included in several locations in a mechanical ventilation circuit (invasive or non-invasive). MinimHal® allows the use of a pMDI or a vibrating mesh nebulizer simultaneously or not.

MinimHal® has four openings. Two of them are for the mechanical ventilation circuit: one for the way in of the gas flow and the other for the way out of the gas flow exit. The other two openings are for plugging a pMDI and a vibrating mesh nebuliser, such as Aerogen® Pro or Aerogen® Solo.


Benefits of the use of MinimHal® spacer:

Connecting both a vibrating mesh nebuliser and a pressurised metered dose inhaler with a single device in a mechanical ventilation circuit through MinimHal® provides significant benefits for ventilated patients and caregivers in critical care units

1. MinimHal® can be used with both a pressurised metered dose inhaler (pMDI) and a vibrating mesh nebuliser. The assembly of the mechanical ventilation circuit is then simplified using one device instead of two.

2. When positioned on the inspiratory branch, MinimHal® does not require to be removed from the circuit thanks to its hermetics caps which ensure the tightness of the circuit

3. In vitro studies performed with the MinimHal® spacer showed a higher aerosol delivery with both the pMDI and the vibrating mesh nebuliser in comparison with T connectors, which are traditionally used.

4. Thanks to its low volume of 60 mL, MinimHal® can be used in both an adult and a pediatric mechanical ventilation circuit.

5. MinimHal®, when it is used with a vibrating mesh nebuliser or a pMDI, does not change the ventilators parameters.

6. Designed with a transparent material, MinimHal® make easier the monitoring of the mechanical ventilation circuit.

7. As it is made of a light material, MinimHal® does not weight on the mechanical ventilation circuit.

8. Thanks to its specific adaptor, MinimHal® can be used with the soft mist inhaler (Respimat®).

In vitro drug delivery obtained with MinimHal® and Aerogen Solo® T piece when using a vibrating mesh nebulizer Aerogen Solo® (Salbutamol MYLAN, 5mL of a 2.5 mg/2.5mL solution) and in vitro drug delivery obtained with MinimHal® and an MDI adapter (Intersurgical) when using a pressurized metered dose inhaler (Ventolin®, GSK, 10 doses of 100 µg). results obtained in a pediatric mechanical ventilation model when devices are inserted on the inspiratory branch. Results are expressed as means ± standards deviations (n=5).

MinimHal : Chambre d'inhalation pour circuit de ventilation mécanique

MinimHal® and COVID-19 : An appropriate spacer

During the Covid-19 pandemic, it is recommended to use an inhaler. MinimHal® enables and facilitates this use on ventilation circuits.

If it not possible to switch from a pMDI treatment to a nebulized treatment, it is then recommended to use a vibrating mesh nebuliser. As its drug tank is isolated from the circuit, it enables to avoid the infection of the drug solution.

MinimHal® can be used with a pMDI as well as a vibrating mesh nebuliser. MinimHal® make it possible to go through a device to another, thus, avoiding to infect the patient environment.

The trademark  MinimHal® belongs to Laboratoire OptimHal-ProtecSom SAS.

The Aerogen® trademark belongs to The Aerogen Company Limited.