Spacer for mechanical ventilation circuit

CombiHaler® Solo is 100% designed and manufactured in France. CombiHaler® Solo is a spacer designed to be used in invasive or non-invasive mechanical ventilation and critical care (ICU). CombiHaler® Solo device allows the administration of medicines by pMDI without disconnecting the circuit and is supposed to be used while a nebulizer is not necessary.

Who is it for ?

It is intended for patients suffering from Chronic Obstructive Pulmonary Disease (COPD), asthma or chronic obstructive respiratory insufficiency in pulmonology, critical care or operating suite.

The CombiHaler® Solo is single use only and is meant to be used in hospital, in intensive care services or for home care.

Why should you use the CombiHaler® Solo spacer ?

CombiHaler® Solo spacer provides significant benefits for ventilated patients and care-givers.

1. Using CombiHaler® Solo in mechanical ventilation circuit allows to save up to 50% of the drug contained in pMDI. Regarding the price of some drugs, it can represent a real benefit.

2. No change of the ventilator settings : reduces the risk of errors. Using the CombiHaler® Solo does not modify the respiratory parameters.

3. As it is transparent, CombiHaler® Solo do not bother the monitoring of the ventilation circuit.

4. As a Single use device, CombiHaler® Solo can be used during the lifespan of the ventilation system.

Scientifcs publications    

Aerosol delivery and Mechanical Ventilation: In vitro evaluation of spacers for use with a pressurized-metered dose inhaler (pMDI) and a vibrating mesh nebulizer (VMN) in comparison with T adapters.

RFMV 2020 : M. Eckes, B. Demouveaux, B. Hervieu, A. Paris, A. Vanlaeys, T. Porée.


Effect of spacer volume on drug delivery using mechanical ventilation: An in vitro study.

RDD 2019 : M. Eckes, T. Porée.


In vitro evaluation of spacers in comparison with T-adapters in mechanical ventilation with pMDI and vibrating mesh nebulizer.

ERS 2019 : M. Eckes, T. Porée.


In vitro evaluation of a spacer in a pediatric model of mechanical ventilation.

CIPP 2015 : N. Boukhettala, T. Porée.


Study of the performances of a new spacer in mechanical ventilation.

ISAM 2013 : N. Boukhettala , T. Porée , P. Diot , L. Vecellio.


Study Of The Effectiveness Of A New Inhalation Chamber In Invasive Mechanical Ventilation. 

ATS 2012 : N. Boukhettala, P. Diot, T. Porée, L. Vecellio.


A new Spacer for pMDI and nebulizers in mechanical ventilation. 

ERS 2012 : N. Boukhettala, P. Diot, T. Porée, L. Vecellio.

Download the CombiHaler® Solo user manual

La marque de commerce CombiHaler® est une marque de ProtecSom-OptimHal SAS.