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CombiHaler® Solo / CombiHaler®

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CombiHaler® Solo and CombiHaler® spacer devices improve aerosol deposition for ventilated adult patients

CombiHaler® is an inhalation chamber designed and manufactured entirely in France for invasive and non-invasive mechanical ventilation circuits. It offers an effective and safe solution for improving medication administration via pressurized metered-dose inhaler and/or vibrating mesh nebulizer without disconnecting the circuit .

CombiHaler ® Solo has the same features as CombiHaler ® , except that it only allows the administration of medication by pressurized metered-dose aerosol.

CombiHaler® Solo and CombiHaler® were manufactured for patients suffering from Chronic Obstructive Pulmonary Disease (COPD), asthma, chronic obstructive pulmonary disease, and other respiratory infections. They are intended for use in pulmonology, intensive care, critical care, and operating room departments .

3 patients under mechanical ventilation

CombiHaler® Solo and CombiHaler® Features

CombiHaler® Solo and CombiHaler® inhalation chambers have two openings designed to be connected to the ventilator circuit, one for the entry of a gas flow and the other for the exit of the gas flow.

Illustration CombiHaler® solo
Illustration CombiHaler® solo - MDI NEB

The use of CombiHaler®

CombiHaler ® also includes an opening for receiving a pressurized metered-dose aerosol and an opening for receiving a sieve nebulizer.

CombiHaler® technical specifications
CombiHaler® particle impact diagrams

CombiHaler® medication loss

The shape of the CombiHaler® Solo and CombiHaler® reduces the impact of medication particles within the inhalation chamber, significantly reducing medication loss.

Can be used with the Respimat inhaler®

Respimat ® (Boehringer Ingelheim) is an inhaler used for the treatment of asthma, chronic obstructive pulmonary disease (COPD) and other respiratory conditions.

The adapter, which can be supplied with the spacer device, allows the use of a Respimat® inhaler with CombiHaler® on a mechanical ventilation circuit. Designed to maintain a tight seal on the circuit, the adapter ensures safe use.

CombiHaler and Respimat inhaler
CombiHaler - proven effectiveness

in vitro tests were conducted in our OptimHal laboratory. These tests proved that:

  1. CombiHaler® and CombiHaler® Solo increase the delivered dose of the medication contained in metered-dose inhalers up to 2 times compared to a T-piece .
  2. CombiHaler ® increases the dose of medication compared to a T-piece available to the patient via nebulization.
  3. CombiHaler® of up to 50% of the nebulized medication (40% with amikacin). For certain substances, particularly antibiotics, this can represent a significant economic advantage.
Did you know that?

In vivo tests have proven that adding a preliminary dose of bronchodilator before nebulizing the drug significantly increases the effective pulmonary dose of the drug nebulized with CombiHaler®.¹

To learn more, access the CombiHaler Solo® and CombiHaler® .

Installation of the CombiHaler® and CombiHaler® Solo in an adult mechanical ventilation circuit

For installation in an adult mechanical ventilation circuit, CombiHaler ® Solo and CombiHaler ® connect to the inspiratory branch before the Y-piece.

CombiHaler Solo mechanical ventilation circuit diagrams
CombiHaler mechanical ventilation circuit diagrams

CombiHaler® Solo and CombiHaler® are manufactured in France, under the ISO 13485:2016 standard, the international standard for medical devices. This certification demonstrates our commitment to adhering to extremely rigorous quality standards in the manufacturing of our devices. This means that our products are designed, manufactured, and tested with meticulous attention to detail to ensure the highest levels of safety and efficacy.

Photo of the caregivers

CombiHaler® Solo and CombiHaler® , at the service of the patient

CombiHaler® Solo and CombiHaler® are inhalation chambers designed to serve the patient and facilitate the work of caregivers .

  1. A simple and quick installation.
  2. It avoids the risk of contamination thanks to its airtight caps and single-use design.
  3. Limits interventions on the ventilation system.
  4. Allows monitoring of the circuit thanks to its transparent material. 
  5. Does not alter ventilatory parameters. 
  6. Can be used for the entire lifespan of the ventilation system.

CombiHaler® Solo and CombiHaler® devices to an adult ventilation circuit

Discover in video how to connect our CombiHaler ® Solo and CombiHaler ® to an adult ventilation circuit before the Y room.

  1. Amal E. Rashad, Yasmin M. Madney, Ahmed M. Abdelhaleem Ali, Mohammad F. Mohammad, Fahad T. Alsulami, Yousef Saeed Alqarni, Rania M. Sarhan & Mohamed EA Abdelrahim (2024) Performance of newly developed add-on devices on aerosol delivery in noninvasive ventilated subjects, Experimental Lung Research, 50:1, 199-207, DOI: 10.1080/01902148.2024.2418555